Ionis Pharmaceuticals ($IONS) Insider Trading & Smart Money Activity

Ionis Pharmaceuticals, Inc. · Biotechnology · Latest filing Jun 26, 2026

Ionis Pharmaceuticals, Inc. ($IONS) has 12 insider trades, 3 13F position changes and 3 analyst ratings on file. In the last 12 months on the open market, no insider bought and 3 insiders sold ($1.88M), net -$1.88M.

Insider buyers (12 mo)
0
Insider sellers (12 mo)
3
Net insider $ (12 mo)
-$1.88M
Congress trades (12 mo)
0
13F moves on file
3
Analyst ratings on file
3

IONS insider buying and selling by quarter

QuarterInsider buysInsider salesCongress buys / sales13F added / cut
Q1 2026 0 0 0 / 0 0 / 0
Q2 2026 0 3 · $1.88M 0 / 0 1 / 2
Q3 2026 0 0 0 / 0 0 / 0
Q4 2026 0 0 0 / 0 0 / 0

Insider buys and sales count open-market trades only (Form 4 codes P and S). Grants, option exercises and tax withholding are left out.

All IONS insider, congress, 13F and analyst activity

DateSourceWhoActionSharesValue / amount ΔOwn1W1M6MFilingStory
Insider Eugene SchneiderEVP, Chf Clinical Develop Ofcr Buy (Option exercise) 26K sh $1.58M +2.5%-31.1% Read
Insider Brett MoniaChief Executive Officer Sell (Option exercise) 50K sh +2.5%-31.1% —
Insider Brett MoniaChief Executive Officer Buy (Option exercise) 50K sh $2.84M +2.5%-31.1% —
Insider Joseph BaroldiEVP, Chief Business Officer Sell (Open-market sale) 10b5-1 5.63K sh $451.70K +2.5%-31.1% —
Insider Joseph BaroldiEVP, Chief Business Officer Buy (Option exercise) 5.63K sh $277.18K +2.5%-31.1% Read
Analyst Leerink Partners Reiterates to buy PT $129 +4.4%-28.6% Read
Insider Eric SwayzeEVP Research Sell (Open-market sale) 10b5-1 10.60K sh $839.47K +4.4%-28.6% —
Insider Brett MoniaChief Executive Officer Sell (Option exercise) 21.07K sh +4.4%-28.6% —
Insider Brett MoniaChief Executive Officer Buy (Option exercise) 21.07K sh $686.95K +4.4%-28.6% —
Analyst HC Wainwright Reiterates to buy PT $130 +4.4%-28.6% Read
Insider Brett MoniaChief Executive Officer Sell (Option exercise) 14.56K sh +3.5%-26.1% Read
Insider Brett MoniaChief Executive Officer Buy (Option exercise) 14.56K sh $474.82K +3.5%-26.1% Read
Analyst Leerink Partners Reiterates to buy PT $122 +3.0%-26.8% Read
Insider Spencer Berthelsen Sell (Open-market sale) 10b5-1 8K sh $587.92K +2.6%-26.0% Read
Insider Spencer Berthelsen Buy (Option exercise) 8K sh $195.36K +2.6%-26.0% —
13F T. Rowe Price Investment Management Reduced -2.95M sh $454.66M +1.8%-0.4% —
13F T. Rowe Price Investment Management Reduced -2.95M sh $496.97M +1.8%-0.4% —
13F Baker Bros. Advisors Added +255.89K sh $162.36M +1.8%-0.4% —

1W / 1M / 6M = how IONS moved from the trade or filing date.

Insider trading in IONS: who is buying and selling

InsiderRoleTradesOpen-market netShares heldLast trade
Brett Monia Chief Executive Officer 6 — Jun 26, 2026
Joseph Baroldi EVP, Chief Business Officer 2 -$451.70K Jun 26, 2026
Eugene Schneider EVP, Chf Clinical Develop Ofcr 1 — Jun 26, 2026
Eric Swayze EVP Research 1 -$839.47K Jun 25, 2026
Spencer Berthelsen 2 -$587.92K Jun 15, 2026

Institutions moving IONS (13F)

Analyst ratings on IONS

DateFirmActionRatingPrice target1W1M6MStory
Leerink Partners Reiterates buy $129 +4.4%-28.6% Read
HC Wainwright Reiterates buy $130 +4.4%-28.6% Read
Leerink Partners Reiterates buy $122 +3.0%-26.8% Read

Frequently asked questions

Are IONS insiders buying or selling?

Over the last 12 months 0 insiders made 0 open-market purchases worth $0 and 3 insiders made 3 open-market sales worth $1.88M, a net -$1.88M.

What is the latest insider trade in IONS?

Eugene Schneider, EVP, Chf Clinical Develop Ofcr filed a buy (option exercise) of 26K sh worth $1.58M on Jun 26, 2026.

Which institutions changed their IONS positions?

Recent 13F filers moving the stock include T. Rowe Price Investment Management and Baker Bros. Advisors.

Other biotechnology stocks

Data comes from public SEC Form 4 and 13F filings and STOCK Act disclosures. Dates are the trade or filing date reported. This page is for research only and is not investment advice.

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