ACOG 10% Owner Opaleye Management Inc. Buys $123K of Stock

Key Points

  • Opaleye Management increased its stake in Alpha Cognition to 3,291,984 shares after this purchase.
  • The stock recently traded around $8.30, which is below its 50-day moving average of $8.94.
  • Analysts have a consensus 'strong buy' rating on Alpha Cognition, with a mean price target of $18.00.

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Not investment advice. TradeTexts is not a registered investment adviser, and this automated Alpha Cognition Inc. Common Stock alert may contain errors. Disclosures

On October 23, 2026, Opaleye Management Inc. bought 14,973 shares of Alpha Cognition Inc. (ACOG) for approximately $123,293.67. This purchase was reported in a Form 4 filing with the SEC. After this transaction, Opaleye's total ownership in Alpha Cognition increased to 3,291,984 shares, reflecting a 0.46% increase in their stake.

ACOG Alpha Cognition Inc. Common Stock
$8.34 +28.31% year to date
Daily close · Oct 23, 2026
Insider trading track record

Opaleye Management Inc. vs. the S&P 500

YTD return +2.13% hypothetical
All-time return +2.13% S&P 500 +1.10%
vs. S&P 500 +1.03% ahead of the index

Hypothetical returns from Opaleye Management Inc.'s disclosed trades, not real profit or advice. How we model this.

What Changed in Opaleye Management's Alpha Cognition Position

Opaleye Management's latest purchase adds 14,973 shares to its holdings in Alpha Cognition. This brings their total to 3,291,984 shares. The transaction occurred at a price of $8.23 per share, just under the closing price of $8.34 on the same day.

Other Institutional Activity in Alpha Cognition

Opaleye Management also reported earlier trades in Alpha Cognition. On October 15, 2026, it bought 22,657 shares, followed by another purchase of 14,283 shares on October 16, 2026. As of June 30, 2026, other institutional investors included Solas Capital Management, which held 1,924,617 shares, and AWM Investment Company, which held 1,672,168 shares.

Alpha Cognition Inc. Common Stock Stock Down 0.1%

Alpha Cognition shares closed at $8.34 on October 23, 2026. The stock is currently trading around $8.30 as of October 26, 2026, which is about 0.5% below its closing price. The shares are also below their 50-day moving average of $8.94 but above their 52-week low of $4.50.

Recent Earnings

For the trailing twelve months, Alpha Cognition reported revenue of about $15.3 million. The company has a negative net margin of -137.7% and a return on equity of -49.5%. The next earnings report is scheduled for November 12, 2026.

Insider Buying and Selling at Alpha Cognition Inc. Common Stock

Recently, Opaleye Management has been active in buying shares of Alpha Cognition. On October 15 and 16, 2026, it acquired 22,657 and 14,283 shares, respectively, at prices of $8.43 and $8.23 per share. These transactions were reported before the latest purchase on October 23.

Analysts Set New Price Targets

Analysts have given Alpha Cognition a strong buy rating. On July 10, 2026, Raymond James initiated coverage with a target price of $20.00. HC Wainwright & Co. maintained a buy rating on August 17, raising their target from $18.00 to $20.00. B. Riley Securities also initiated coverage on August 20, setting a target of $21.00.

About Alpha Cognition

Alpha Cognition Inc. is a biopharmaceutical company based in Grapevine, Texas. It focuses on developing treatments for neurodegenerative diseases, including Alzheimer's disease. This recent insider activity comes as the company continues its growth in the biotechnology sector.

Bottom Line

Opaleye Management's recent share purchases in Alpha Cognition show their increasing confidence in the company. Investors should keep an eye on the upcoming earnings report on November 12, 2026, and watch for any further insider transactions or analyst updates.

Source: Opaleye Management Inc.'s Form 4 filing on $ACOG (Oct 23, 2026). Written by software, not financial advice. How we make alerts

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