Wells Fargo Cuts Intuitive Surgical (ISRG) Price Target to $486

Wells Fargo reiterated its Overweight rating on Intuitive Surgical, Inc. on October 21, 2026, while adjusting its price target from $487 to $486. The update came during a busy session where multiple Wall Street firms revisited their views on the medical equipment provider following its latest financial reports.

ISRG Intuitive Surgical, Inc.

$438 ▼ -22.06% year to date

1M 3M YTD

Daily close · Oct 20, 2026

Wells Fargo's Call on Intuitive Surgical, Inc.

In its research note on October 21, 2026, Wells Fargo maintained its positive stance on the stock while trimming its target by one dollar. The firm's Overweight rating suggests analysts expect the healthcare provider to perform better than its peers in the sector.

Intuitive Surgical, Inc. Stock Down 0.5%

Intuitive Surgical, Inc. recently traded around $424.71 as of October 21, 2026. The stock closed at $438.00 on October 20, 2026.

Recent Earnings

Intuitive Surgical reported trailing-twelve-month revenue of $11.03 billion and an earnings per share of $8.85. The firm generated a net profit margin of 28.4% and a return on equity of 17.4%.

Insider Buying and Selling at Intuitive Surgical, Inc.

Insiders completed several transactions leading up to the analyst updates. On August 21, 2026, officer Mark Preston Brosius sold 154 shares valued at $59,439. Later, on September 9, 2026, Brosius sold 69 shares worth $24,671, followed by a sale of 48 shares valued at $17,141 on September 11, 2026. Additionally, officer Fredrik Widman sold 1,089 shares at a price of $374.44 per share for a total of $407,765 on September 15, 2026.

Analysts Set New Price Targets

Several firms updated their views on ISRG on October 21, 2026. Evercore ISI Group maintained an In-Line rating with a target moved from $400.00 to $385.00. TD Cowen reiterated a Buy rating with a target of $485.00. Barclays maintained an Overweight rating, raising its target from $485.00 to $500.00. RBC Capital maintained an Outperform rating while lowering its target from $575.00 to $550.00. Overall, the stock carries a consensus Buy recommendation from 30 analysts with a mean price target of $478.53.

About Intuitive Surgical, Inc.

Headquartered in Sunnyvale, California, Intuitive Surgical, Inc. builds advanced robotic systems that assist surgeons with complex, minimally invasive procedures. Its flagship technology helps healthcare providers expand access to precise surgical care around the world.

Bottom Line

Investors continue to monitor Wall Street sentiment and upcoming financial reports to gauge how robotic surgery adoption impacts company growth. Watch for the next scheduled earnings release for further updates on operational performance.