Rtw Investments 13F Holdings & Latest Moves

13F filer · Latest filing May 15, 2026 · SEC CIK 0001493215

Rtw Investments reported a 13F portfolio worth $10.05B as of Q1 2026. Latest 13F moves (filed May 15, 2026): 13 new positions, 40 added, 14 reduced. Largest change by value: added $ARGX ($658.20M held).

13F value (Q1 2026)
$10.05B
New positions
13
Added / reduced
40 / 14
Sold out
0

Top buys and sells in the latest 13F

Biggest new and added positions

FiledTicker MoveChangeShares heldValue held1W1M6MStory
$ARGX Added +35.95K (+5.34%) 709.45K $658.20M +0.9%+10.6% Read
$CGON Added +4.97M (+247.14%) 6.98M $496.27M -4.0%-11.0% Read
$TNGX Added +11.81M (+791.92%) 13.30M $433.07M -1.6%+60.0% Read
$CGON Added +4.97M (+247.14%) 6.98M $416.02M -4.0%-11.0% Read
$APGE Added +70K (+2.58%) 2.78M $369.27M 0.0%+6.2% Read

Biggest reduced and exited positions

FiledTicker MoveChangeShares heldValue held1W1M6MStory
$NTRA Reduced -250K (-16.67%) 1.25M $333.81M +9.0%+16.4% Read
$COGT Reduced -2.13M (-28.10%) 5.46M $211.25M -0.0%+1.5% Read
$COGT Reduced -2.13M (-28.10%) 5.46M $180.68M -0.0%+1.5% Read
$APLS Reduced -3.98M (-51.93%) 3.69M $151.20M Read
$ZLAB Reduced -385K (-5.53%) 6.57M $124.91M -9.6%-13.9% Read

New positions in the latest 13F

FiledTicker MoveChangeShares heldValue held1W1M6MStory
$CADL New +6.42M 6.42M $66.53M -8.9%-2.4% Read
$CADL New +6.42M 6.42M $54.97M -8.9%-2.4% Read
$AKTS New +1.59M 1.59M $52.27M +4.0%+5.8% Read
$AKTS New +1.59M 1.59M $33.48M +4.0%+5.8% Read
$WAY New +1.63M 1.63M $33.46M +9.1%+3.5% Read
$WAY New +1.63M 1.63M $29.96M +9.1%+3.5% Read
$DNTH New +248.06K 248.06K $24.18M +0.4%-4.2% Read
$IPSC New +8.70M 8.70M $21.30M -3.4%-1.7% Read
$DNTH New +248.06K 248.06K $20.36M +0.4%-4.2% Read
$AVTX New +856.96K 856.96K $15.84M -7.8%-17.7% Read
$DFTX New +300K 300K $14.11M +7.2%+13.2% Read
$OCGN New +6.67M 6.67M $10.20M -3.6%-12.2% Read
$OCGN New +6.67M 6.67M $8.07M -3.6%-12.2% Read

Added positions in the latest 13F

FiledTicker MoveChangeShares heldValue held1W1M6MStory
$ARGX Added +35.95K (+5.34%) 709.45K $658.20M +0.9%+10.6% Read
$CGON Added +4.97M (+247.14%) 6.98M $496.27M -4.0%-11.0% Read
$TNGX Added +11.81M (+791.92%) 13.30M $433.07M -1.6%+60.0% Read
$CGON Added +4.97M (+247.14%) 6.98M $416.02M -4.0%-11.0% Read
$APGE Added +70K (+2.58%) 2.78M $369.27M 0.0%+6.2% Read
$CELC Added +2.49M (+452.50%) 3.04M $313.86M +0.4%-35.9% Read
$ERAS Added +16.01M (+10917.43%) 16.16M $296M +9.9%+41.1% Read
$RDNT Added +346.50K (+8.80%) 4.29M $264.26M +3.8%+8.9% Read
$RDNT Added +346.50K (+8.80%) 4.29M $243M +3.8%+8.9% Read
$ESTA Added +66.86K (+2.58%) 2.66M $227.89M +9.8%+28.1% Read
$ERAS Added +16.01M (+10917.43%) 16.16M $227.01M +9.9%+41.1% Read
$IRTC Added +486.51K (+41.16%) 1.67M $198.47M +2.2%-0.2% Read
$STOK Added +76.67K (+1.38%) 5.62M $184M -2.5%-0.3% Read
$STOK Added +76.67K (+1.38%) 5.62M $167.69M -2.5%-0.3% Read
$RGEN Added +142K (+13.35%) 1.21M $164.55M +11.8%+27.2% Read
$RGEN Added +142K (+13.35%) 1.21M $157.49M +11.8%+27.2% Read
$HNGE Added +1.58M (+445.97%) 1.93M $157.26M +1.4%+25.4% Read
$CMPS Added +1.88M (+21.41%) 10.63M $150.45M +13.9%+13.7% Read
$IMTX Added +1.44M (+12.56%) 12.87M $130.37M +6.9%-13.2% Read
$CMPS Added +1.88M (+21.41%) 10.63M $122.59M +13.9%+13.7% Read
$RARE Added +648.66K (+21.62%) 3.65M $121.83M -6.4%+1.5% Read
$IMTX Added +1.44M (+12.56%) 12.87M $120.71M +6.9%-13.2% Read
$RARE Added +648.66K (+21.62%) 3.65M $88.85M -6.4%+1.5% Read
$ISRG Added +118.77K (+117.33%) 220K $87.49M +4.0%-1.1% Read
$CNTA Added +263.34K (+14.70%) 2.05M $83.19M +0.4%+0.4% Read
$REPL Added +216.56K (+3.03%) 7.36M $81.44M -5.9%+71.6% Read
$CSTL Added +643.10K (+30.40%) 2.76M $65.79M +5.3%+8.0% Read
$REPL Added +216.56K (+3.03%) 7.36M $65.33M -5.9%+71.6% Read
$CSTL Added +643.10K (+30.40%) 2.76M $57.97M +5.3%+8.0% Read
$CRNX Added +100K (+7.40%) 1.45M $54.31M +0.1%-4.5% Read
$AQST Added +1.18M (+18.82%) 7.43M $30.97M -1.2%+1.2% Read
$AQST Added +1.18M (+18.82%) 7.43M $30.89M -1.2%+1.2% Read
$EVMN Added +218.56K (+17.03%) 1.50M $29.79M -0.2%-9.1% Read
$FLGT Added +583.97K (+82.83%) 1.29M $26.45M +9.0%+16.9% Read
$FLGT Added +583.97K (+82.83%) 1.29M $24.08M +9.0%+16.9% Read
$EVMN Added +218.56K (+17.03%) 1.50M $19.96M -0.2%-9.1% Read
$CMPX Added +1.69M (+67.46%) 4.19M $8.62M +11.3%+9.7% Read
$CMPX Added +1.69M (+67.46%) 4.19M $8.37M +11.3%+9.7% Read
$MIST Added +3.82M (+152.62%) 6.33M $8.29M -6.0%-12.7% Read
$MIST Added +3.82M (+152.62%) 6.33M $8.17M -6.0%-12.7% Read

Reduced positions in the latest 13F

FiledTicker MoveChangeShares heldValue held1W1M6MStory
$NTRA Reduced -250K (-16.67%) 1.25M $333.81M +9.0%+16.4% Read
$COGT Reduced -2.13M (-28.10%) 5.46M $211.25M -0.0%+1.5% Read
$COGT Reduced -2.13M (-28.10%) 5.46M $180.68M -0.0%+1.5% Read
$APLS Reduced -3.98M (-51.93%) 3.69M $151.20M Read
$ZLAB Reduced -385K (-5.53%) 6.57M $124.91M -9.6%-13.9% Read
$QURE Reduced -1.13M (-30.31%) 2.59M $120.07M -10.6%+3.0% Read
$ZLAB Reduced -385K (-5.53%) 6.57M $112.22M -9.6%-13.9% Read
$TSHA Reduced -2.72M (-16.58%) 13.68M $93.16M -7.9%+0.2% Read
$TSHA Reduced -2.72M (-16.58%) 13.68M $78.11M -7.9%+0.2% Read
$SYK Reduced -145K (-59.18%) 100K $33.05M +3.2%+0.4% Read
$BBNX Reduced -500K (-20%) 2M $31.34M +24.9%+52.0% Read
$BBNX Reduced -500K (-20%) 2M $29.06M +24.9%+52.0% Read
$JBIO Reduced -876.07K (-60.45%) 573.21K $12.74M -4.9%-31.1% Read
$JBIO Reduced -876.07K (-60.45%) 573.21K $8.79M -4.9%-31.1% Read

All tracked 13F moves by Rtw Investments

FiledTicker MoveChangeShares heldValue held1W1M6MStory
$ZLAB Reduced -385K (-5.53%) 6.57M $112.22M -9.6%-13.9% Read
$ZLAB Reduced -385K (-5.53%) 6.57M $124.91M -9.6%-13.9% Read
$WAY New +1.63M 1.63M $33.46M +9.1%+3.5% Read
$WAY New +1.63M 1.63M $29.96M +9.1%+3.5% Read
$OCGN New +6.67M 6.67M $10.20M -3.6%-12.2% Read
$OCGN New +6.67M 6.67M $8.07M -3.6%-12.2% Read
$DNTH New +248.06K 248.06K $20.36M +0.4%-4.2% Read
$DNTH New +248.06K 248.06K $24.18M +0.4%-4.2% Read
$DFTX New +300K 300K $14.11M +7.2%+13.2% Read
$IPSC New +8.70M 8.70M $21.30M -3.4%-1.7% Read
$CADL New +6.42M 6.42M $66.53M -8.9%-2.4% Read
$CADL New +6.42M 6.42M $54.97M -8.9%-2.4% Read
$AVTX New +856.96K 856.96K $15.84M -7.8%-17.7% Read
$AKTS New +1.59M 1.59M $33.48M +4.0%+5.8% Read
$AKTS New +1.59M 1.59M $52.27M +4.0%+5.8% Read
$QURE Reduced -1.13M (-30.31%) 2.59M $120.07M -10.6%+3.0% Read
$TSHA Reduced -2.72M (-16.58%) 13.68M $78.11M -7.9%+0.2% Read
$TSHA Reduced -2.72M (-16.58%) 13.68M $93.16M -7.9%+0.2% Read
$SYK Reduced -145K (-59.18%) 100K $33.05M +3.2%+0.4% Read
$NTRA Reduced -250K (-16.67%) 1.25M $333.81M +9.0%+16.4% Read
$JBIO Reduced -876.07K (-60.45%) 573.21K $8.79M -4.9%-31.1% Read
$JBIO Reduced -876.07K (-60.45%) 573.21K $12.74M -4.9%-31.1% Read
$COGT Reduced -2.13M (-28.10%) 5.46M $180.68M -0.0%+1.5% Read
$COGT Reduced -2.13M (-28.10%) 5.46M $211.25M -0.0%+1.5% Read
$BBNX Reduced -500K (-20%) 2M $31.34M +24.9%+52.0% Read
$BBNX Reduced -500K (-20%) 2M $29.06M +24.9%+52.0% Read
$APLS Reduced -3.98M (-51.93%) 3.69M $151.20M Read
$RARE Added +648.66K (+21.62%) 3.65M $121.83M -6.4%+1.5% Read
$TNGX Added +11.81M (+791.92%) 13.30M $433.07M -1.6%+60.0% Read
$STOK Added +76.67K (+1.38%) 5.62M $184M -2.5%-0.3% Read
$STOK Added +76.67K (+1.38%) 5.62M $167.69M -2.5%-0.3% Read
$RGEN Added +142K (+13.35%) 1.21M $157.49M +11.8%+27.2% Read
$REPL Added +216.56K (+3.03%) 7.36M $81.44M -5.9%+71.6% Read
$RGEN Added +142K (+13.35%) 1.21M $164.55M +11.8%+27.2% Read
$REPL Added +216.56K (+3.03%) 7.36M $65.33M -5.9%+71.6% Read
$RDNT Added +346.50K (+8.80%) 4.29M $243M +3.8%+8.9% Read
$RARE Added +648.66K (+21.62%) 3.65M $88.85M -6.4%+1.5% Read
$RDNT Added +346.50K (+8.80%) 4.29M $264.26M +3.8%+8.9% Read
$MIST Added +3.82M (+152.62%) 6.33M $8.29M -6.0%-12.7% Read
$MIST Added +3.82M (+152.62%) 6.33M $8.17M -6.0%-12.7% Read
$IRTC Added +486.51K (+41.16%) 1.67M $198.47M +2.2%-0.2% Read
$ISRG Added +118.77K (+117.33%) 220K $87.49M +4.0%-1.1% Read
$IMTX Added +1.44M (+12.56%) 12.87M $120.71M +6.9%-13.2% Read
$IMTX Added +1.44M (+12.56%) 12.87M $130.37M +6.9%-13.2% Read
$HNGE Added +1.58M (+445.97%) 1.93M $157.26M +1.4%+25.4% Read
$FLGT Added +583.97K (+82.83%) 1.29M $26.45M +9.0%+16.9% Read
$FLGT Added +583.97K (+82.83%) 1.29M $24.08M +9.0%+16.9% Read
$EVMN Added +218.56K (+17.03%) 1.50M $19.96M -0.2%-9.1% Read
$EVMN Added +218.56K (+17.03%) 1.50M $29.79M -0.2%-9.1% Read
$ESTA Added +66.86K (+2.58%) 2.66M $227.89M +9.8%+28.1% Read
$ERAS Added +16.01M (+10917.43%) 16.16M $296M +9.9%+41.1% Read
$ERAS Added +16.01M (+10917.43%) 16.16M $227.01M +9.9%+41.1% Read
$CSTL Added +643.10K (+30.40%) 2.76M $57.97M +5.3%+8.0% Read
$CRNX Added +100K (+7.40%) 1.45M $54.31M +0.1%-4.5% Read
$CMPX Added +1.69M (+67.46%) 4.19M $8.62M +11.3%+9.7% Read
$CMPS Added +1.88M (+21.41%) 10.63M $150.45M +13.9%+13.7% Read
$CMPX Added +1.69M (+67.46%) 4.19M $8.37M +11.3%+9.7% Read
$CMPS Added +1.88M (+21.41%) 10.63M $122.59M +13.9%+13.7% Read
$CGON Added +4.97M (+247.14%) 6.98M $416.02M -4.0%-11.0% Read
$CGON Added +4.97M (+247.14%) 6.98M $496.27M -4.0%-11.0% Read
$CNTA Added +263.34K (+14.70%) 2.05M $83.19M +0.4%+0.4% Read
$CELC Added +2.49M (+452.50%) 3.04M $313.86M +0.4%-35.9% Read
$CSTL Added +643.10K (+30.40%) 2.76M $65.79M +5.3%+8.0% Read
$ARGX Added +35.95K (+5.34%) 709.45K $658.20M +0.9%+10.6% Read
$AQST Added +1.18M (+18.82%) 7.43M $30.89M -1.2%+1.2% Read
$AQST Added +1.18M (+18.82%) 7.43M $30.97M -1.2%+1.2% Read
$APGE Added +70K (+2.58%) 2.78M $369.27M 0.0%+6.2% Read

13F reports are filed quarterly, up to 45 days after the quarter ends, so they show past holdings. 1W / 1M / 6M = how the stock moved after the filing.

Stocks Rtw Investments holds or traded

Frequently asked questions

What did Rtw Investments buy and sell in its latest 13F?

It opened or added to $ARGX, $CGON, $TNGX, $CGON and $APGE; it cut or exited $NTRA, $COGT, $COGT, $APLS and $ZLAB.

Data comes from public SEC Form 4 and 13F filings and STOCK Act disclosures. Dates are the trade or filing date reported. This page is for research only and is not investment advice.

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